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Neonatal testing for karyotypic common aneuploidies is performed upon specific clinician request (using the referral form) in order to provide a result. Neonates (<3 months of age) with clinical features suggestive of trisomy 13 (Patau syndrome), trisomy 18 (Edwards syndrome), or trisomy 21 (Down syndrome), etc. The testing is targeted the possibility to análissis of additional numeric chromosome abnormalities.If the aneuploidy result is abnormal, karyotyping of metaphase cells will be performed to confirm the result.